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Scientist - Cell Line Development

Institution Agenus
City Cambridge
Country United Kingdom
Job Title Scientist - Cell Line Development
Description Summary:
We have an exciting opportunity for a Scientist to join our new Cell Line Development Team in Cambridge.
This is a state of the art facility located in the centre of Cambridge specialised in the development of biopharmaceuticals of Immuno Oncology targets.
You will be part of a global team, with opportunities to grow with the company.

Conducting stable cell line development projects, including design, partial execution in timely manner, reporting to Molecule Project Teams.
•Liaise and coordinate CLD projects with Process Development and Process Analytical groups.
•Serve as Subject Matter Expert on Project Teams for early and late-stage projects.
•Author and review documents in support of regulatory filings from IND/CTA to BLA.
•Develop, evaluate and implement new technologies, methods and third party technology for process improvement.
•Write working instructions or SOPs, technical reports and mentor junior staff.
•Aid in the preparation and presentation of publications, presentations, regulatory documents and/or primary inventor of patents.
•Liaise closely with collaborators and sites globally, maintain clear and efficient communication.
•Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug, GxP compliance, where applicable.

Category Research
Keywords Cell Line
Education MSc with industrial experience (2-5 years) in relevant field or PhD in a biological science/biochemistry discipline.
Experience Experience in mammalian cell culture techniques (adherent and suspension cells, CHO, HEK) in various scales, from multi-wells to small scale bioreactors.
•Experience in efficient transfections and selection of highly expressing stable cell lines, single cell cloning, evaluation of cell lines for productivity and product quality, cell banking. Experience with using FACS or ClonePix in developing monoclonal antibody expressing cell lines is a bonus.
•Skills in molecular biology: construction of expression vectors, evaluation of expression and stability enhancing elements.
•Experience with automation in cell line development and product analysis is highly desirable.
•Experience with evaluation of cell line stability, both at the cell culture and genetic level.
•Experience in an industrial setting is preferable.
Work experience  
Primary Language English
Secondary Language  
Other Requirements Ability to work autonomously and in a team.
•Highly autonomous and productive in performing laboratory experiments or method development.
•Outstanding organizational and multi-tasking skills; able to manage several projects/cell lines simultaneously.
•Ability to effectively work on multiple project teams and changing project priorities.
•Excellent writing and communication skills, good attention to details.
•Supervise and mentor scientific staff as well as communicate effectively to senior management as appropriate.
Comments Please feel free to apply online here:
Job created Mar 08, 2017 21:06:31
Job last modified Mar 09, 2017 09:25:16